Physiology - Autonomics and Cardiovascular

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  1. Which of the following statements correctly describes the parasympathetic nervous system?
  2. Your answer:
    long post-ganglionic neurons innervate arterioles and veins
    pre-ganglionic and post-ganglionic neurons utilize acetylcholine as their neurotransmitter
    post-ganglionic neurons exert their effects on adrenergic receptors in the target tissues
    pre-ganglionic fibers originate in the thoracic spinal cord
    activation causes dilation of the pupils


  3. Chromaffin cells in the adrenal medulla release:
  4. Your answer:
    nitric oxide
    acetylcholine
    angiotension II
    nicotine
    epinephrine


  5. Which of the following contains a correct sequence of blood flow through the heart?
  6. Your answer:
    pulmonary veins, left atrium, left A-V valve, left ventricle, aortic valve
    right atrium, right ventricle, mitral valve, aorta, systemic vasculature
    super vena cava, tricuspid valve, right atrium, right A-V vavle, right ventricle
    right ventricle, aortic valve, aorta, systemic vasculature, inferior vena cava, left atrium
    left ventricle, pulmonary valve, pulmonary artery, lungs, right atrium, right ventricle


  7. In a healthy individual at rest, which of the following conditions applies?
  8. Your answer:
    the volume of blood pumped per minute from the left heart is equal to the volume of blood pumped per minute from the right heart
    blood flow in the pulmonary vasculature is less than blood flow in the systemic vasculature
    blood flow to all tissues and organs is equal
    the pressure generated by the left ventricle is equal to the pressure generated by the right ventricle
    none of the above


  9. Phase 2 of the action potential in cardiac ventricular cells is primarily due to increased membrance permeability to:
  10. Your answer:
    calcium
    cAMP
    sodium
    potassium
    chloride


  11. Desmosomes in the intercalated discs of the myocardium are most important during muscle contraction because they contribute to:
  12. Your answer:
    sequestration of calcium
    cell-cell adhesion
    aerobic capacity
    myocyte contractility
    cell-cell transmission of action potentials


  13. In the electrocardiogram, the QRS complex represents the:
  14. Your answer:
    depolarization of the SA node
    depolarization of the ventricles
    repolarization of the ventricles
    delay at the AV node
    depolarization of the atria


  15. If action potential propagation at the AV node was blocked, which of the following events would you expect to observe?
  16. Your answer:
    slowing of the rate of contraction of the ventricles
    increased rate of contraction of the ventricles
    increased rate of contraction of the atria
    ventricular fibrillation
    none of the above


  17. Which of the following statements regarding the pacemaker potential of SA node cells is true?
  18. Your answer:
    the rate of depolarization of pacemaker cells is intrinsic and cannot be modulated
    pacemaker cells have a resting membrane potential that is close to the potassium equilibrium potential
    pacemaker cells will not depolarize in the absence of sympathetic stimulation
    the pacemaker potential is caused by potassium entering the cell via slow channels
    the pacemaker potential is slower in achieving threshold when acetylcholine is applied


  19. The second heart sound ('dub') follows the T wave of the ECG and is directly caused by which of the following events:
  20. Your answer:
    repolarization of the atria
    closing of the aortic and pulmonary valves
    contraction of the ventricles
    repolarization of the ventricles
    closing of the A-V valves


  21. Ventricular pressure exceeds aortic pressure during which phase or phases of the cardiac cycle?
  22. Your answer:
    isovolumetric ventricular contraction and ventricular ejection
    ventricular ejection only
    isovolumetric ventricular relaxation
    atrial systole only
    diastole and atrial systole


  23. Sympathetic stimulation increases cardiac output by which of the following mechanisms?
  24. Your answer:
    it slows the rate of pacemaker depolarization of cells in the SA node
    it increases venous tone by vasoconstriction
    it decreases the rate of cross-bridge cycling in ventricular cells
    it decreases total blood valume
    a and d


  25. Arterial pressure is maintained during diastole by:
  26. Your answer:
    contraction of the atria during late diastole
    depolarization of the ventricles
    turbulent fluid flow following constriction of the arteries
    recoil of the elastic walls of the arteries
    decreased peripheral resistance following ventricular relaxation


  27. Which of the following best describes the anatomical and functional characterisitcs of the capillaries as compared with other vessel beds?
  28. Your answer:
    capillaries are lined by smooth muscle cells
    capillaries are the site of the greatest flow velocity
    all capillaries have fenestrations to permit exchange of nutrients and waste products
    capillaries are highly elastic vessels
    capillaries provide the largest total cross-sectional area of the vascular beds


  29. Blood pressure is being measured using the auscultatory method. When are the first sounds heard in a stethoscope that is placed below the cuff?
  30. Your answer:
    when cuff pressure equals mean arterial pressure
    when the A-V valves close
    when the aortic and pulmonary valves close
    when cuff pressure equals diastolic pressure
    at peak systole


  31. Vasodilation of arterioles would:
  32. Your answer:
    a and c
    favor filtration of plasma into the interstitial fluid
    none of the above
    increase flow of lymph
    favor resorption of fluid into capillaries


  33. Active hyperemia refers to:
  34. Your answer:
    decreased blood flow to tissues that results in vasodilation
    decreased blood flow to tissues that results in vasoconstriction
    increased metabolic activity that results in vasoconstriction
    increased oxygen demand that results in increased blood vessel growth
    increased metabolic activity that results in vasodilation


  35. Blood vessels in the skin:
  36. Your answer:
    respond primarily to metabolic regulation of flow
    dilate in response to systemic sympathetic activation
    lack capillary beds
    dilate in response to sympathetic modulation form the hypothalamus
    have a high resting arteriolar tone


  37. Which of the following statements correctly applies to the areterial baroreceptors:
  38. Your answer:
    increased firing causes an increase in sympathetic activity
    they detect increases and decreases in arterial blood pressure
    they are located in the medulla
    they fire in response to relaxation of arteriolar smooth muscle cells
    they decrease firing in response to stretch of the arterial walls


  39. With a few minutes after donation of 1 pint of whole blood to a blood bank, which of the following would be decreased compared with pre-donation values?
  40. Your answer:
    heart rate
    a and d
    the percentage of cardiac output flowing to the kidneys
    total peripheral resistance
    stroke volume


  41. Which of the following variables will be increased immediately following henmorrhage, compared with pre-hemorrhage values?
  42. Your answer:
    heart rate
    cardiac output
    venous return
    firing of baroreceptors
    all of the above


  43. Which of the following does not contribute to increased stroke volume during exercise:
  44. Your answer:
    increased end-diastolic volume
    increased contractility of cardiac muscle
    increased venous return
    increased length of filling time during diastole
    increased sympathetic stimulation of ventricular muscle


  45. During acute episodes of moderate exercise in a healthy individual, blood flow to the heart is:
  46. Your answer:
    increased
    unchanged
    decreased
    shunted to the pulmonary circulation
    insufficient to maintain a faster contraction rate


  47. Severe hypotension can lead to which of the following?
  48. Your answer:
    prolonged increase in sympathetic discharge to all tissues
    increased blood flow to skin and kidneys
    chronic pain
    increased urine production
    decreased heart rate


  49. The principle mechanism of anaphylactic (allergic) shock is:
  50. Your answer:
    a large increase in fluid loss from the lymph nodes
    prolonged vasodilation due to release of histamine
    prolonged vasoconstriction due to release of angiontensin II
    decreased fluid volume due to dehydration
    prolonged vasoconstriction due to release of histamine


  51. Physical endurance training increases a person's:
  52. Your answer:
    maximal cardiac output
    maximal heart rate
    resting blood pressure
    resting heart rate
    all of the above


  53. Which of the following might be prescribed to alleviate hypertension? (read carefully)
  54. Your answer:
    an alpha-adrenergic receptor agonist (mimetic)
    an anti-diuretic
    a beta-adrenergic receptor antagonist (blocker)
    a cholinergic receptor antagonist (blocker)
    adrenaline


  55. Ventricular wall thickening can be caused by which of the following?
  56. Your answer:
    hypertention
    hemorrhage
    chronic endurance exercise
    a and c
    all of the above


  57. The driving pressure for blood flow in the right coronary artery is:
  58. Your answer:
    greater than that in the left coronary artery
    less than that in the left coronary artery
    equal to that in the left coronary artery
    less than that in the pulmonary artery
    b and d


  59. Atherosclerosis:
  60. Your answer:
    results in thinning of the arterial walls
    can cause ventricular fibrillation
    is alleviated by treatment with vasoconstrictor drugs
    is typically associated low blood levels of cholesterol and heavy exercise
    is associated with decreased coronary vessel resistance



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