Pediatric Seizures

Ghazala Q. Sharieff, MD, FACEP, FAAP, FAAEM

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  1. A 2-1/2 year old child has a 5 minute generalized tonic-clonic seizure with a fever of 102. Examination reveals a right otitis media, no nuchal rigidity and normal mental status one hour after the event. Neurodevelopmental status is normal. Family history is positive for maternal febrile seizures. This is the child's first seizure. Which of the following statements are true?
  2. Your answer:
    An EEG should be performed in one week
    The risk of recurrence of a febrile seizure in this child is approximately 30%.
    A lumbar puncture should be performed
    Phenobarbital should be initiated.


  3. What is the fastest rate that phenytoin can be administered intravenously in a child?
  4. Your answer:
    3mg/kg/min
    2mg/kg/min
    50mg/min
    1mg/kg/min


  5. All of the following statements are true Except:
  6. Your answer:
    Felbamate has been associated with aplastic anemia and liver toxicity.
    Fosphenytoin cannot be given IM due to severe pain at the injection site.
    Fosphenytoin can be given at an IV rate of 3mg/min.
    Lamotrigine can lead to rash development, however there is no report of serious


  7. Simple febrile seizures are defined as all of the following Except:
  8. Your answer:
    Only two seizures in a 24 hour period
    No evidence of CNS infection
    Generalized seizure lasting < 15 minutes
    Age range 6 months to 5 years.


  9. Which of the following is not a risk factor for febrile seizure recurrence?
  10. Your answer:
    Family history of febrile seizures
    Age less than 24 months of age with onset of first febrile seizure
    Age less than 12 months of age with onset of first febrile seizure
    Temperature less than 40C with febrile seizure


  11. The pediatric doses of Lorazepam is 0.05-0.1 mg/kg
  12. Your answer:
    TrueFalse


  13. The pediatric doses of Diazepam is rectal 0.5mg/kg, IV:0.2-0.3mg/kg
  14. Your answer:
    TrueFalse


  15. The pediatric loading dose of phenobarbital is 15-20 mg/kg
  16. Your answer:
    TrueFalse


  17. The pediatric loading dose of phenytoin is 15-20 mg/kg
  18. Your answer:
    TrueFalse


  19. The pediatric loading dose of fosphenytoin: IV/IM 15-20 mg PE (phenytoin equivalents)/kg
  20. Your answer:
    TrueFalse


  21. The pediatric does of Midazolam is rectal 0.5mg/kg: IV: 0.1mg/kg: IM: 0.2mg/kg
  22. Your answer:
    TrueFalse


  23. A 3-month old female presents with a generalized seizure which has been present for 25 minutes. The seizure is refractory to rectal valium given by the paramedics and Ativan in the ED. Her temperature is 36.5C. There is no sign of trauma. Mother reports that she just started the baby on formula this week. All of the following are true except:
  24. Your answer:
    Patients with hyponatremic seizures typically have prolonged seizures
    Patients with hyponatremic seizures tend to have higher temperatures than infants with seizures
    The mother should be questioned regarding exact formula preparation
    Hyponatremia may be corrected by using 4-5cc/kg of 3% saline


  25. The risk of development of epilepsy in the general populations is approximately 1% by age 7 years. In children with simple febrile seizures, the incidence of epilepsy is:
  26. Your answer:
    No different that the rate in the general population
    Only slightly higher than the rate in the general population
    30-50 times that of the general population
    10 times that of the general population


  27. The latest ACEP article on febrile seizures recommends the following in regards to lumbar puncture for patients with febrile seizures:
  28. Your answer:
    A lumbar puncture can be deferred in patients less than 18 months of age with a simple febrile
    A CT scan should be performed prior to performing a lumbar puncture
    All patients less than 12 months of age should undergo lumbar puncture
    All patients less than 18 months of age should undergo a lumbar puncture


  29. Which of the following is the most common cause of seizures in children?
  30. Your answer:
    Head injury
    Fever
    Hypoxia
    Metabolic disturbances
    Ischemia


  31. Which of the following is the drug of choice for neonatal seizures?
  32. Your answer:
    Phenobarbital
    Fosphenytoin
    Valproic acid
    Phenytoin


  33. Which of the following causes of gastroenteritis have been associated with seizures?
  34. Your answer:
    Shigella
    Campylobacter
    Salmonella
    Rotavirus



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